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9780824726898

Acute Care Of The Cancer Patient

by ;
  • ISBN13:

    9780824726898

  • ISBN10:

    0824726898

  • Format: Hardcover
  • Copyright: 2005-08-18
  • Publisher: CRC Press

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Summary

Univ. of Texas MD Andersen Cancer Center, Houston, TX. Provides knowledge and expertise on acute medical care for cancer patients receiving chemotherapy. Describes the general principles of oncological practice, perioperative care of patients undergoing cancer resection surgery, and pediatric issues. For practitioners.

Table of Contents

Introduction v
Preface vii
Contributors xxi
Cancer Growth, Progression, and Metastasis
1(10)
Jerald J. Killion
Isaiah J. Fidler
Evolution of the Primary Tumor
1(1)
Tumor Angiogenesis
2(1)
Determinants of Metastasis
3(1)
Implications for Therapy of Cancer
4(7)
References
6(5)
Principles of Clinical Cancer Staging
11(6)
S. Eva Singletary
Introduction
11(1)
Principles of Clinical Cancer Staging Using the TNM System
12(1)
Changes in the TNM-Staging System
13(2)
Conclusions
15(2)
References
15(2)
Principles of Surgical Cancer Care
17(14)
Janice N. Cormier
Raphael E. Pollock
Introduction
17(1)
Historical Perspective
17(1)
Patient Assessment
18(1)
Roles for Surgery
19(8)
Reconstruction and Rehabilitation
27(1)
The Surgical Oncologist
27(1)
Conclusions
28(3)
References
28(3)
Principles of Chemotherapy
31(12)
Silwan Chedid
Jonathan Trent
Introduction
31(1)
Tumor Growth
31(1)
Chemotherapy and the Cell Cycle
32(1)
Combination Chemotherapy
32(1)
Dosage Intensity
33(1)
Drug Resistance
33(1)
Chemotherapeutic Agents
34(7)
Definition of Response
41(1)
Conclusion
41(2)
References
41(2)
Endocrine Evaluation and Management of the Perioperative Cancer Patient
43(26)
Steven Waguespack
Robert F. Gagel
Mario Maldonado
Rajagopal V. Sekhar
Ashok Balasubramanian
Introduction
43(1)
Management of the Cancer Patient with Diabetes Mellitus
43(5)
Management of the Cancer Patient with Thyroid Disease
48(3)
Disorders of the Adrenal Gland
51(4)
Hypercalcemia and Hypocalcemia
55(2)
Perioperative Management of the Patient with Pituitary Disease
57(12)
References
65(4)
Principles of Bioimmunotherapy: Interferon, Interleukins, Growth Factors, Monoclonal Antibodies, Antisense
69(24)
Yolanda Gutierrez-Puente
Arturo Chavez-Reyes
Saroj Vadhan-Raj
Xinsheng Liao
James L. Murray
Paula Trahan-Rieger
Introduction
69(1)
Definition and Classification of Biotherapy
70(15)
Biotherapy-Related Side Effects
85(1)
Conclusions
86(7)
References
86(7)
Bone Marrow Transplantation Complications Requiring Therapy in the Intensive Care Unit
93(14)
Humberto Caldera
James Gajewski
Introduction
93(1)
Outcome of Bone Marrow Transplantation Recipients Requiring Intensive Care
94(1)
Diffuse Alveolar Hemorrhage
94(1)
Viral Pneumonias
95(2)
Cytomegalovirus Pneumonia
97(1)
Posterior Reversible Leukoencephalopathy Syndrome (PRES)
98(1)
Transfusion Issues in Bone Marrow Transplant Recipients
99(1)
Thrombotic Thrombocytopenic Purpura (TTP)
99(1)
Central Venous Catheter-Related Complications
100(1)
Mucositis
101(6)
References
101(6)
Palliative Radiotherapy: Clinical and Radiobiologic Considerations
107(38)
Nora A. Janjan
Introduction
107(2)
Palliative Radiation Techniques
109(36)
References
137(8)
Clinical Trials in Oncology: Organization and Oversight
145(10)
Carleen A. Brunelli
Leonard A. Zwelling
Philosophy and Principles of Clinical Research
145(1)
Institutional Review Boards and the Department of Health and Human Services
146(2)
Scientific Review
148(1)
Quality Assurance
149(2)
Institutional Culture
151(1)
Education Programs
152(1)
Conclusions
153(2)
References
153(2)
Clinical Trials in Oncology: Study Design
155(10)
Lyle D. Broemeling
Introduction
155(1)
Clinical Trial Design
156(4)
Clinical Trials in Anesthesiology and Critical Care
160(3)
Conclusions
163(2)
References
163(2)
Clinical Trials in Oncology: Ethical Issues
165(12)
Martin L. Smith
Anne L. Flamm
Timothy M. Pawlik
Introduction
165(1)
Historical Background
166(1)
The Doctrine and Process of Informed Consent
167(2)
Study Design, Subject Selection, and Monitoring
169(2)
Research on Terminally Ill Patients
171(1)
Placebo Controls
172(1)
Conflicts of Interest
172(2)
Conclusion
174(3)
References
174(3)
General Principles of Perioperative Medicine: Surgical and Medical Perspectives
177(8)
Gregory H. Botz
Zdravka Zafirova
Introduction
177(1)
Principles of Medical Management in the Perioperative Period
177(2)
Perioperative Management
179(6)
References
181(4)
The Stress Response and Immunomodulation
185(16)
A. C. Carr
George M. Hall
Background
185(1)
The Stress Response and Immunomodulation
186(1)
The Neuroendocrine Stress Response and Surgery
186(3)
Insulin Resistance
189(1)
The Cytokine and Acute Phase Responses
190(1)
Cell-Mediated Immunity
191(1)
Modulating the Stress Response: Why Bother?
191(1)
Anesthetic and Critical Care Perspectives
192(2)
Surgical Perspectives
194(7)
References
195(6)
Inflammation, Coagulation, and Endothelial Dysfunction: Implications in Perioperative Care
201(16)
Ravi Taneja
Davy C. H. Cheng
Introduction
201(1)
Inflammation
201(3)
Coagulation
204(2)
Endothelial Dysfunction: A Chef d'Oeuvre Par Excellence
206(1)
Therapeutic Interventions
207(2)
Inflammation and Carcinogenesis
209(1)
Conclusion
210(7)
References
210(6)
Suggested Readings
216(1)
Perioperative Care of the Immunocompromised Patient
217(14)
Sandra L. Peake
Dhaval R. Ghelani
Introduction
217(1)
Immunosuppression Associated with Cancer
217(1)
Anesthetic Perspectives
218(2)
Intensive Care Perspectives
220(5)
Surgical Perspectives
225(2)
Conclusions
227(4)
References
227(3)
Suggested Readings
230(1)
Anesthesia for the Chronic Pain Patient
231(12)
Arun Rajagopal
Hemant N. Shah
Introduction
231(1)
Implications for the Anesthesiologist
232(1)
Basic Definitions
232(1)
Preanesthetic Evaluation
233(1)
Intraoperative Anesthetic Considerations
234(2)
Postoperative Considerations
236(2)
Intensive Care Issues
238(1)
Clinical Examples
238(2)
Conclusions
240(3)
References
240(1)
Suggested Readings
241(2)
Preoperative Anesthesia Evaluation
243(16)
Tayab R. Andrabi
Marc A. Rozner
Introduction/Background
243(1)
Goals of Preoperative Evaluation
244(2)
Chemotherapy and Radiation Therapy
246(3)
The Cancer Patient with Heart Disease
249(5)
The Cancer Patient with an Implanted Cardiac Generator
254(1)
Summary
255(4)
References
255(4)
Perioperative Management of Brain Tumors
259(40)
Rashmi N. Muller
Background
259(1)
Intracranial Dynamics and the Effects of Anesthetics
259(9)
Epidemiology of Brain Tumors
268(1)
Presentation of Patients with Brain Tumors
268(3)
Diagnosis
271(1)
Surgical Principles
272(1)
Preoperative Considerations
273(1)
Intraoperative Management
274(7)
Emergence
281(1)
Postoperative Considerations After Craniotomy
282(3)
Infratentorial Surgery
285(2)
Ventriculoperitoneal Shunting
287(1)
Surgery for Pituitary Tumors
288(3)
Emergency Craniotomy for Brain Tumors
291(8)
References
291(8)
Perioperative Management of Spinal Tumors
299(10)
Robert J. Bohinski
Laurence D. Rhines
Ziya Gokaslan
History and Physical Examination
299(1)
Patient Positioning
300(3)
Intraoperative Neurologic Monitoring
303(1)
Postoperative Neurologic Monitoring
304(1)
Coagulation Abnormalities/Blood Loss
304(1)
Antibiotic Prophylaxis
305(1)
Malnutrition
306(1)
Prevention of Thromboembolism
306(1)
Pain Control
306(3)
References
307(2)
Perioperative Care of Patients with Head and Neck Cancer
309(12)
Andrew MacLachlan
David Ferson
Kristen Pytynia
Ed Diaz
N. Nguyen
W. Botnick
Introduction
309(1)
Preoperative Evaluation
310(1)
Intraoperative Management
311(4)
Postoperative Care
315(2)
Conclusion
317(4)
References
317(4)
Perioperative Care for Thoracic Neoplasms in Acute Cancer Medicine
321(42)
Jay B. Brodsky
John L. Chow
Jessica S. Donington
Introduction
321(1)
Anesthesia Perspectives
321(4)
Intrathoracic Malignancies
325(2)
Surgical Perspectives
327(6)
Critical Care Perspectives
333(11)
Conclusions
344(19)
References
344(19)
Anesthetic Management of Cardiac Tumors
363(8)
Dilip Thakar
Ashish Sinha
Clinical Presentation
363(1)
Specific Cardiac Tumors
364(2)
Extracardiac Tumors with Cardiac Involvement
366(2)
Diagnostic Methods
368(1)
Anesthetic Management of Cardiac Tumors
368(3)
References
369(2)
Perioperative Care of Patients with Liver Neoplasms
371(14)
James F. Arens
Debra L. Kennamer
Portal Venous Embolization
374(1)
Anesthetic Management
374(3)
Surgical Management
377(2)
Outcome After Liver Resection
379(1)
Laparoscopic Liver Resection
379(1)
Radiofrequency Tissue Ablation
379(1)
Percutaneous RFA
380(1)
Complications of Percutaneous RFA
381(1)
Laparoscopic RFA
381(1)
Ethanol Injection Therapy
381(1)
Hepatic Artery Infusion
382(3)
References
382(3)
Perioperative Care for Major Abdominal Surgery: Stomach, Pancreas, Small Intestine, Colon, Rectum, Anus
385(22)
Karen Chen
Peter Hsu
Introduction
385(1)
Anesthesiologist's Concerns
385(5)
Surgical Concerns
390(7)
Complications/Perioperative Concerns
397(1)
Conclusions
398(9)
References
398(9)
Perioperative Care of Patients with Endocrine Neoplasms
407(26)
M. F. M. James
D. M. Dent
Pituitary Tumors
407(5)
Parathyroid Tumors
412(2)
Gastroenteropancreatic Tumors
414(4)
Surgical Aspects
418(2)
Pheochromocytoma
420(4)
Multiple Endocrine Neoplasia
424(1)
Conclusions
425(8)
References
425(8)
Perioperative Care for Breast and Gynecological Neoplasms
433(22)
Troy S. Browne
Anees Chagpar
Kelly K. Hunt
Pedro Ramirez
Perioperative Care of Breast Cancer
433(9)
Perioperative Care of Gynecologic Cancer
442(13)
References
450(5)
Postanesthesia Care for Reconstructive Microvascular Surgery
455(10)
Michael J. Miller
Principles of Reconstructive Microvascular Surgery
455(1)
Postanesthesia Care
456(7)
Summary
463(2)
References
463(2)
Perioperative Care of Patients with Musculoskeletal Neoplasms
465(20)
Thao P. Bui
Alan W. Yasko
Introduction
465(1)
General Principles
465(3)
Anesthesia Perspectives
468(2)
Surgical Management
470(2)
Anesthesia Management
472(7)
Intensive Care and Postoperative Perspectives
479(1)
Conclusions
479(6)
References
480(5)
Perioperative Care of Intraoperative Chemotherapy and Radiation: Limb and Peritoneal Perfusion Procedures
485(14)
Richard E. Royal
Paul F. Mansfield
Introduction
485(1)
Operative Procedures
486(3)
Intraoperative Issues
489(3)
Postoperative Issues
492(2)
Chemotherapy Specific Complications
494(2)
Summary
496(3)
References
496(3)
Anesthesia for the Patient in Remote Diagnostic and Therapeutic Locations
499(6)
John C. Frenzel
Introduction
499(1)
Managing Clinical Structure
499(1)
Site Assessment
500(1)
Equipment
500(1)
Mobile Carts
500(1)
Physically Remote Situations
501(1)
Communication
501(1)
Documentation Standards
501(1)
Preoperative and Postoperative Evaluations
502(1)
Anesthetic Management
502(1)
Sedation
502(1)
Deep Sedation
503(1)
General Anesthesia
503(1)
Future Directions and Trends
504(1)
Conclusions
504(1)
References
504(1)
Oncologic Emergencies: Pulmonary Embolus, Superior Vena Cava Syndrome, Cardiac Tamponade, and Respiratory Emergencies
505(14)
Nicole D. Switzer
Arun Rajagopal
Introduction
505(1)
Pulmonary Embolus
505(3)
Superior Vena Cava (SVC) Syndrome
508(2)
Cardiac Tamponade
510(2)
Respiratory Emergencies
512(7)
References
516(1)
Suggested Readings
517(2)
Transfusion Therapy and the Cancer Patient
519(18)
Lawrence T. Goodnough
George Despotis
Current Blood Risks
519(6)
Blood Transfusion
525(3)
Platelet Transfusions
528(3)
Conclusion
531(6)
References
531(6)
Principles of Medical ICU Oncology
537(8)
Spencer S. Kee
Introduction
537(1)
Anesthesia Team Perspective
538(1)
Oncology Team Perspective
539(1)
Intensive Care Team Perspective
540(1)
Conclusions
541(4)
References
541(4)
Delirium and Substance Withdrawal
545(14)
Alan D. Valentine
Jacqueline Bickham
Introduction
545(1)
Prevalence
546(1)
Clinical Presentations of Delirium
546(1)
Causes of Delirium
547(1)
Assessment of Delirium
548(1)
Management
549(2)
Substance Withdrawal
551(8)
References
554(5)
Neutropenia and Sepsis in Cancer Patients
559(8)
Kenneth V. I. Rolston
Edward B. Rubenstein
Introduction
559(1)
Infection in Neutropenic Patients
559(2)
Infections in Non-Neutropenic Patients
561(2)
Device-Related Infections
563(1)
Special Considerations
564(1)
Summary
565(2)
References
565(2)
Acute Coronary Syndrome in Cancer Patients
567(12)
S. Wamique Yusuf
Edward T. H. Yeh
Introduction/Background
567(1)
Acute Coronary Syndrome
568(1)
Etiology of ACS in Cancer Patients
568(1)
Presentation
569(1)
Risk Stratification
569(1)
Examination
569(1)
Investigations
569(2)
Special Problems in Cancer Patients
571(1)
Complications of Myocardial Infarction
572(1)
Ventricular Fibrillation
573(1)
Prophylaxis
573(1)
Treatment
573(1)
Ventricular Tachycardia
573(1)
Management Strategies for Ventricular Tachycardia
574(1)
Heart Failure and Low-Output Syndromes
574(1)
Management of Right Ventricular Ischemia/Infarction
575(1)
Mechanical Defects After Acute Myocardial Infarction
575(4)
References
576(3)
Critical Care of the Cancer Patient with Pulmonary Infiltrates
579(90)
Vickie R. Shannon
Burton F. Dickey
Introduction
579(1)
Infectious Pulmonary Complications Among Critically Ill Patients with Cancer
580(28)
Noninfectious Pulmonary Complications Among Critically Ill Patients with Cancer
608(42)
Summary
650(19)
References
650(19)
Acute Renal Failure
669(28)
John R. Foringer
Andrew D. Shaw
Kevin W. Finkel
Defining Acute Renal Failure
669(1)
Evaluation of Acute Renal Failure
670(1)
Classification of Acute Renal Failure
671(3)
Obstructive (Postrenal) Nephropathy
674(2)
Intrinsic Acute Renal Failure
676(5)
Tubulointerstitial Nephritis
681(4)
Acute Renal Failure Associated with Lymphoma and Leukemia
685(1)
Radiation Nephritis
685(1)
Prevention of Acute Tubular Necrosis
686(1)
Treatment of Acute Tubular Necrosis
687(2)
Renal Replacement Therapy
689(8)
References
690(7)
Complications of Bone Marrow Transplantation and Immunosuppression
697(16)
Shubhra Ghosh
Daniel R. Couriel
Acute Graft-Versus-Host Disease
697(4)
Prevention of Acute GvHD
701(1)
Management of Acute GvHD
701(1)
Chronic GvHD
702(2)
Management of Chronic GvHD
704(9)
References
705(8)
Sedation in the ICU
713(30)
Lisa E. Connery
Douglas B. Coursin
Patients with Malignancy
714(1)
The ICU Experience from the Perspective of the Cancer Patient
715(1)
Terminal Sedation
715(1)
Sedation
716(1)
Anxiety
716(1)
Agitation
716(1)
Delirium
717(1)
Environment
717(1)
Sedation and the Stress Response
718(1)
The Ideal ICU Sedative
718(1)
Goals of Sedation
718(1)
Sedation Monitoring
719(1)
Sedation Scales
719(1)
Clinical Sedation Monitoring
719(1)
Subjective Sedation Scales
720(2)
Neuromuscular Blockade
722(1)
Objectived Sedation Monitoring
722(1)
Auditory Evoked Potentials
723(1)
Choice of Sedative
724(1)
SCCM Guidelines for Sedatives
724(1)
Benzodiazepines
724(1)
Midazolam
725(2)
Lorazepam
727(1)
Lorazepam and Propylene Glycol Toxicity
728(1)
Diazepam
728(1)
Flumazenil
728(1)
Propofol
729(1)
Comparative Studies
730(1)
Propofol and Brain Injury
730(1)
Propofol in Children
730(1)
Dexmedetomidine
731(1)
Pharmacokinetic Properties
731(1)
DEX in the ICU
731(1)
Haloperidol
732(1)
Protocol for Continuous Infusion of Haloperidol
733(1)
Other Agents
734(1)
Etomidate
734(1)
Barbiturates
734(1)
Ketamine
734(1)
Analgesia
735(1)
Opioids
735(1)
Remifentanil
736(1)
Fentanyl
736(1)
Hydromorphone
736(1)
Morphine Sulfate
736(1)
Naloxone
736(1)
Drug Interactions in Cancer Patients
736(1)
Cost Considerations
737(1)
Post-ICU Depression and Stress Syndromes
737(1)
Withdrawal Syndromes
738(1)
Removal of Life Support
738(1)
The Future of Intensive Care Sedation
739(4)
References
739(4)
Cardiovascular Support
743(16)
M. Fanshawe
S. G. Tan
Jeff Lipman
Introduction
743(1)
Hemodynamic Monitoring
744(4)
Causes of Circulatory Failure in Oncology Patients
748(1)
Perioperative Optimization
749(1)
Treatment of Circulatory Failure
750(3)
Conclusion
753(6)
References
754(5)
Respiratory Failure and Mechanical Ventilation in Cancer Patients
759(46)
Todd Kelly
Etiologies of Respiratory Failure in Cancer Patients
759(2)
Prognosis of Mechanical Ventilation in Cancer Patients
761(4)
Management of Respiratory Failure
765(15)
Weaning
780(7)
Advanced Ventilation
787(3)
Terminal Weaning
790(15)
References
792(13)
Nutrition Support of the ICU Cancer Patient
805(22)
Tami Johnson
Anne Tucker
Todd Canada
Introduction
805(1)
Assessing and Monitoring Nutritional Status
805(2)
Determination of Energy and Protein Needs
807(4)
Enteral Versus Parenteral Nutrition
811(3)
Nutrition Support in Special Patient Populations
814(1)
Hepatic Failure
814(4)
Renal Failure
818(2)
Pulmonary Failure
820(2)
Summary
822(5)
References
822(5)
Nosocomial Infections and Antibiotic Therapy in Patients with Cancer
827(20)
Amar Safdar
Issam I. Raad
Introduction
827(3)
Bloodstream Infections
830(5)
Pneumonia
835(12)
References
839(8)
Critical Care Imaging in Oncology Patients
847(26)
Chaan S. Ng
Sanjay Singh
Mylene T. Truong
Comparison of Imaging Modalities
847(1)
Thoracic Imaging
848(3)
Cardiopulmonary Disorders
851(7)
Abdominopelvic Disorders
858(6)
Central Nervous System Disorders
864(9)
References
869(4)
Interventional Radiology in the Oncologic Critical Care Setting
873(18)
Michael J. Wallace
Introduction
873(1)
Drainage Procedures
873(5)
Arterial Interventions
878(4)
Venous Interventions
882(9)
References
885(6)
Care at the End of Life
891(18)
C. Lee Parmley
Introduction/Background
891(2)
Planning Terminal Care
893(4)
Decisions in EOL Care
897(4)
Conflicts over Terminal Care
901(2)
Physician-Assisted Death (PAD) in the United States and Elsewhere
903(2)
Conclusion
905(4)
References
905(4)
Legal Considerations: Liability, Consent, Risk Management, Withdrawing Life Support
909(10)
I. McLellan
J. Tring
Introduction
909(1)
Liability
909(1)
Consent
910(3)
Risk Management
913(2)
Withdrawing Life Support
915(1)
Conclusion
916(3)
References
916(3)
Perioperative Care of Children with Cancer: An Overview
919(4)
Alan I. Fields
Rodrigo Mejia
James D. Wilkinson
References
921(2)
Perioperative Care of Children with Cancer
923(32)
Kerri J. George
Nancy L. Glass
Introduction
923(1)
Anesthetic Perspectives
924(8)
Preoperative Assessment
932(4)
Intraoperative Management
936(4)
Postoperative Care
940(1)
Specific Clinical Cases
941(4)
Anesthesia Outside the Operating Room
945(1)
Do Not Resuscitate Orders and the Terminally ill Child
946(1)
Chronic Pain in the Pediatric Cancer Patient
946(4)
Conclusion
950(5)
References
950(5)
Perioperative Care of Children with Cancer: Intensive Care Perspectives
955(28)
H. Michael Ushay
Bruce M. Greenwald
Introduction
955(1)
General Principles of Perioperative Care
955(4)
System-Specific Issues in the Care of the Perioperative Pediatric Oncology Patient in the PICU
959(6)
Approach to Perioperative Cardiovascular and Organ System Support
965(3)
Cardiovascular Support and Shock
968(3)
The Neurosurgical Oncology Patient
971(4)
Conclusion
975(8)
References
975(8)
Pediatric Surgical Oncology
983(8)
Martin L. Blakely
Richard J. Andrassy
Introduction
983(1)
Supportive Care for Non-Solid Tumors
983(1)
Diagnosis of Solid Tumors
984(2)
Resection of Solid Tumors
986(2)
Surgical Therapy for Solid Tumor Metastases
988(1)
Involvement in Clinical and Basic Research
989(2)
References
989(2)
Symptom Assessment
991(14)
Anthony H. Risser
Karen O. Anderson
Tito R. Mendoza
Charles S. Cleeland
Introduction
991(1)
Multidimensional Symptom Assessment
992(1)
Step One: Initial Identification of Symptoms
993(1)
Step Two: Assessing Symptom Severity/Intensity
994(3)
Step Three: Assessing Symptom Characteristics
997(1)
Step Four: Assessing Symptom Functional Impact
998(1)
Implementation of Symptom Assessment
999(6)
References
1000(5)
Pathophysiology of Cancer Pain
1005(24)
P. M. Dougherty
Introduction
1005(1)
Pain from Uninjured Tissue
1005(8)
Hyperalgesia Following Tissue Injury and Inflammation
1013(3)
Hyperalgesia Following Nerve Injury
1016(4)
Summary
1020(9)
References
1020(9)
Epidemiology of Pain and Cancer-Related Symptoms
1029(10)
Cielito C. Reyes-Gibby
Charles S. Cleeland
Introduction
1029(1)
Epidemiology and Descriptive Research: Prevalence of Cancer Pain and Other Cancer-Related Symptoms
1029(3)
Factors Associated with Inadequate Treatment and Control of Pain and Other Symptoms
1032(1)
Improving Control of Cancer Pain and Other Cancer-Related Symptoms
1032(2)
Limitations of Literature on Cancer-Related Symptoms
1034(1)
Future Directions: Research and Treatment
1035(4)
References
1036(3)
Perioperative Pain in Cancer Patients
1039(24)
Alicia Kowalski
Denise Daley
Thao P. Bui
Peter Norman
Background
1039(2)
Anesthetic Perspectives
1041(14)
Surgical Perspectives
1055(2)
ICU Perspectives
1057(1)
Conclusions
1058(5)
References
1058(3)
Suggested Readings
1061(2)
Cancer Pain
1063(32)
Hemant N. Shah
Allen W. Burton
Oscar de Leon-Casasola
Introduction
1063(1)
Epidemiology
1063(1)
Cancer Pain Data
1064(1)
Assessment
1065(1)
Screening Instruments
1065(3)
Classification of Cancer Pain
1068(5)
Treatment
1073(15)
Summary
1088(7)
References
1089(6)
Palliative Care
1095(16)
Suresh K. Reddy
Ahmed Elsayem
Rudranath Talukdar
Principles of Symptom Control: Assessment and Treatment
1095(12)
Conclusion
1107(4)
References
1107(4)
Index 1111

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